Upping Runes Question

Hey all, I'm kind of a noob and was wondering if people often up runes to try to get to higher runes. I know low runes are a waste of time. But mid runes like

Pul and up for example. If you have lots of

Pul/

Um/

Mal/

Ist, upping them slowly trying to get to like

Lo/

Sur/

Ber for example. Do people do that much or do they mostly use those mid runes just for trading?

No, buy higher runes with lower ones. Like you can usually get an

Ist if you offer

Mal+

Um

Its a lot. It looks deceptively small at first glance, but to get

Ber from

Pul you need about 512

Pul (*2 for

Um * 2 for

Mal * 2 for

Ist etc - it's 2 to the power of "number of steps" when you start from

Pul). You could get more than 100

Ist from 500

Pul when trading which is 3

Ber

Lo at the moment. When starting to cube from

Ist you would need 64

Ist to get

Ber which is actually worth more than 2

Ber when trading. You need to cube 4

Lo to get

Ber, but you can get

Ber for 3

Lo when trading etc

It's kind of ok to cube

Pul ->

Um,

Mal ->

Ist,

Gul ->

Vex,

Ohm ->

Lo,

Sur ->

Ber (because you don't lose much value or you don't lose value at all). It's a huge waste of value when cubing

Ist ->

Gul,

Lo ->

Sur,

Ber ->

Jah,

Jah ->

Cham (especially this one ),

Cham ->

Zod

Ahh, yeah that all makes sense. Ok thanks guys