question about poison tick damage and -res/+psn dam

Trying to understand how poison damage gets calculated, re: equipment that reduces poison resistances and increases poison skill damage.

For example, when biting with

Rabies, I understand that you want as high skill as possible (e.g.,

Plague Bearer+5

Rabies / Spirit shield), but then you want to swap to your alt set that includes weapons like

Death's Web and Bile/psn facet shield.

Is it that the Bite sets the # poison damage / X seconds, and then each tick takes into account the -psn res?

When does +psn skill damage come into play? At the time of the

Rabies bite? Or for each tick?

Would you want the Bile jewel in the

Plague Bearer for the

Rabies bite or in the weapon/shield swap? If +psn damage applies at time of Bite, and -res at time of ticks, presumably you'd want a full set of psn jewels in both weapon/shield swaps. No?

While we are at it, does the 451 psn dam charms apply to

Rabies bites or just weapon attacks? And if the latter, would it apply to Fury attacks?

Thanks!

this is the Pandora box you want to open. i use this guide here for poison:
https://maxroll.gg/d2/resources/poison-damage
I think the +% skill damage is applied initially, to be more precise, when the bit rate is calculated. but the - poison res is applied per frame.

Things I am just learning:

https://www.theamazonbasin.com/wiki/ind ... ill_Damage

https://maxroll.gg/d2/resources/poison-damage

Poison damage from multiple sources is very complicated.

I'm also leanring that Venom from Grief or Treachery can do strange things to poison skills and potentially overwrite an ongoing poisoning. SMH. My plan was

Rabies/Fury druid swapping to Grief/Facet shield after Bite, but Grief (and barb Merc was going to have Grief + Plague, too) might overwrite the

Rabies...